Kids and Diabetes Risk: Do Chromosomes Hold New Clues?

Scientists may be able to identify children at high risk of type 2 diabetes through genetic indicators known as biomarkers.  Researchers with the USDA Agricultural Research Service Children’s Nutrition Research Center at Baylor College of Medicine in Houston may have developed such biomarkers.  These researchers are conducting fine-scale mapping of the genes on a region of chromosome 13, building on earlier work reported in the Journal of Clinical Endocrinology and Metabolism in 2007.  In the previous research, scientists identified a region that influences fasting glucose levels.  The region on chromosome 13 was found in an examination of the DNA and fasting blood glucose tests of 1,030 Hispanic children, ages four to 19 years.  This fine-scale mapping revealed biomarkers that could indicate a predisposition to type 2 diabetes in not only Hispanic youngsters but possibly children of other racial or ethnic groups.  Earlier studies found that this chromosomal region was also associated with risk of obesity in adults, but had not yet been connected with type 2 diabetes risk.  The researchers will present the results of their mapping study in October at the annual national meeting of the Obesity Society in San Diego.

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Categories: Health News Tags: Risk, Risk Chromosomes
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